Plasma Enterolignan Concentrations and Colorectal Cancer Risk in a Nested Case-Control Study

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Original Contribution Plasma Enterolignan Concentrations and Colorectal Cancer Risk in a Nested Case-Control Study

Enterolignans are biphenolic compounds that possess several biologic activities whereby they may influence carcinogenesis. The authors investigated the association between plasma enterolactone and enterodiol and colorectal cancer risk in a Dutch prospective study. Among more than 35,000 participants aged 20–59 years, 160 colorectal cancer cases were diagnosed after 7.5 years of follow-up (1987–...

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Risk Factors for Falls in Hospital In-Patients: A Prospective Nested Case Control Study

Background Patient falls are considered a challenge to the patient’s safety in hospitals, which, in addition to increasing the length of stay and costs, may also result in severe injuries or even the death of the patient. This study aims to investigate the associations between risk factors among fallers in comparison with the control group.   Methods A prospective nested...

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Plasma Organochlorines and Subsequent Risk of Prostate Cancer in Japanese Men: A Nested Case–Control Study

BACKGROUND Although accumulating evidence suggests that exposure to organochlorine pesticides and polychlorinated biphenyls (PCBs) may contribute to the development of prostate cancer, few investigations have used biological samples to classify exposure to specific organochlorines. To our knowledge, this is the first prospective study to investigate the association between blood levels of organ...

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Vitamin D Receptor Gene Polymorphism and the Risk of Colorectal Cancer: A Nested Case-Control Study

Epidemiological and experimental evidence suggest that vitamin D is protective against the risk of colorectal cancer. Polymorphisms in the gene encoding vitamin D receptor (VDR), which mediates most of the known cellular effects of vitamin D, have been suggested to alter this association. Here, using a tag SNP approach, we comprehensively evaluated the role of common genetic variants in VDR and...

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Plasma and dietary carotenoids, and the risk of prostate cancer: a nested case-control study.

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ژورنال

عنوان ژورنال: American Journal of Epidemiology

سال: 2007

ISSN: 0002-9262,1476-6256

DOI: 10.1093/aje/kwm349